Tender Cvs Niallhaslam

Niall Haslam

Post-Doctoral Research Fellow. EMBL Heidelberg.

Niall Haslam is computational biologist, involved in making software tools for biologists. Currently he is employed by the European ProteomeBinders project to create a resource for the selection of epitopes for the design of binding reagents against the human proteome. He has contributed to the development of an ontology to describe protein affinity reagents (http://www.ebi.ac.uk/ontology-lookup/browse.do?ontName=PAR), this work is currently under review in the Human Proteomics Organisation's document review process before final admission into the Proteomic Standards Initiative. Niall trained as a biologist with a degree in Human Genetics from Nottingham. After a year working in the pharmaceutical company Galen (), he took a Masters in Bioinformatics at Exeter University. There he completed a project, with Chris Southan (then at Oxford Glycosciences) working on DNA sequence databases, trying to discover sequences published in patent databases but not found in the more common sequence databases. After his Masters, Niall worked on his PhD in the University of Southampton on DNA sequencing. The project focused on the potential of novel sequencing methods to uncover variation in highly variable genomes. Since the end of 2006 Niall has been working at the EMBL Heidelberg.

At the EMBL Heidelberg, in the group of Toby Gibson, Niall has worked on the use of webservices and other internet based technologies to provide multiple sources of information for researchers in a single resource. As a software developer, Niall has been interested in the potential of these new technologies to share information in a more open manner. Through this Niall has gained an insight into the requirements of the developer community for the next generation of scientific data sharing tools.

Peer-reviewed publications:

  1. An Analysis of the Feasibility of Short Read Sequencing, N. E.Whiteford, N. Haslam, G. Weber, A. Prügel-Bennett, J. W. Essex, P. L. Roach, M. Bradley and C. Neylon, 2005 Nuc. Acids. Res. 33 19 e171
  2. Thermal Equivalence of DNA Duplexes Without Melting Temperature Calculation, G. Weber, N. Haslam, N. Whiteford, A. Prügel-Bennett, J. W. Essex and C. Neylon 2006, Nat. Phys. 2:55–59
  3. Optimal probe length varies for targets with high sequence variation: Implications for probe library design for resequencing highly variable genes N. Haslam, N. Whiteford, G.Weber, A. Prügel-Bennett, J. W. Essex and C. Neylon, 2008, PLoS One, 3(6):e2500
  4. A Novel Method for Whole Genome Repeat Visualisation, N. E.Whiteford, N. Haslam, G. Weber, A. Pr¨ugel-Bennett, J. W. Essex and C. Neylon, 2008, Journal of Complex Systems 17 4:381–398
  5. Understanding eukaryotic linear motifs and their role in cell signaling and regulation. Diella, F., Haslam, N., Chica, C., Budd, A., Michael,S., Brown, N.P., Trave, G. and Gibson, T.J. 2008 Front Biosci. May 1;13:6580-603.
  6. Thermal equivalence of DNA duplexes for probe design. Gerald Weber, Niall Haslam, Jonathan W. Essex and Cameron Neylon. 2008 J. Phys.: Condens. Matter in press.
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